Why is ethanol not used in SN2 reactions?

Risposta:

Ethanol is a polar protic solvent.

Spiegazione:

#S_N2# reactions "favor" certain conditions, just like #S_N1, E_1,#e #E_2# Le reazioni.

Favorable conditions for bimolecular nucleophilic substitution reactions include polar aprotico solvents. Polar protic solvents hinder #S_N2# reactions, as they can hydrogen bond to nucleophiles and make them less effective in attacking the substrate. Ethanol is a polar protic solvent (though alcohols are only weakly acidic). It is commonly seen as a solvent/nucleophile (solvolysis) in #S_N1# Le reazioni.

Lascia un commento